肿瘤防治研究2009，Vol.36Issue(7)：609-611,3.DOI:10.3971/j.issn.1000-8578.2009.07.020
两种化疗方案在宫颈癌同步放化疗中的疗效及副反应对比分析
Two Different Chemotherapy for Concurrent Chemotherapy and Radiotherapy in Cervial Cancer-analysis of Curative Effect and Toxicity
李秀芳 1林丽红 1田卫红 1高雁荣 1申静 1张晶晶1
作者信息
摘要
Abstract
Objective Two chemotherapies were compared in order to investigate the better chemothrapy in concurrent chemotherapy and radiotherapy of cervial cancer. Methods Two hundred and thirty-eight patients with advanced cervical cancer were randomly divided into BIP group(133 cases)and PF group (105 cases). The survival rates and toxicity of these two groups were compared. Results The 2-year sur-vival rate and progression-free survival rate of BIP group was 76.7 % (102/133) and 70.7% (94/133) re-spectively. The 2-year survival rate and progression-free survival rate of PF group was 63.8% (67/105) and 57.1% (60/105) respectively. Signifcant differences were found between these two groups(P< 0.05). Ⅲ～Ⅳ degree myelosuppression occurred more frequently in the BIP group than in PF group(P <0.05). However the long-term toxicity of these two groups has no signifcant difference. Conclusion Of the two chemotherapies used in concurrent chemotherapy and radiotherapy of cervix cancer,BIP proceded PF in survival rate,but it has severer marrow toxicity. The long-term toxicity of these two groups has no signifcam difference关键词
宫颈癌/同步放化疗/生存率Key words
Cervial cancer/Concurrent chemotherapy and radiotherapy/Survival rate分类
医药卫生引用本文复制引用
李秀芳,林丽红,田卫红,高雁荣,申静,张晶晶..两种化疗方案在宫颈癌同步放化疗中的疗效及副反应对比分析[J].肿瘤防治研究,2009,36(7):609-611,3.
