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纤维蛋白原活性在冠心病发展中的作用

赵国胜 杨会杰 周志泳 张嘉晴

中国病理生理杂志2001,Vol.17Issue(1):61-63,3.
中国病理生理杂志2001,Vol.17Issue(1):61-63,3.

纤维蛋白原活性在冠心病发展中的作用

Role of fibrinogen activity in the progress of coronary artery disease

赵国胜 1杨会杰 1周志泳 1张嘉晴1

作者信息

  • 1. 皖南医学院心血管功能研究所, 安徽 芜湖 241001
  • 折叠

摘要

Abstract

AIM: To detect the role of fibrinogen activity (Fa) in theprogress of coronary artery disease (CHD).METHODS:Fa was measured with hemorheology methods in patients with CHD stable phase (n=30) and angina pectoris (n=27).RESULTS: (1) Levels of plasmatic fibrinogen and plasmatic viscosity in patients with CHD were higher than that of control group (P<0.01,P<0.05).(2)Fa and platelet aggregation activity (Pt max, Pt H, Pt K) in patients with CHD angina pectoris were very much higher than that of control group (P<0.01, respectively).(3)There was a negative correlation between PT max, Pt H and Fa(r=-0.8379,P<0.01;r=-0.8784,P<0.01 respectively) in patients with CHD angina pectoris.CONCLUSION: Fa may play a role in the progress of CHD.

关键词

纤维蛋白原/血小板聚集/动脉粥样硬化

分类

医药卫生

引用本文复制引用

赵国胜,杨会杰,周志泳,张嘉晴..纤维蛋白原活性在冠心病发展中的作用[J].中国病理生理杂志,2001,17(1):61-63,3.

中国病理生理杂志

OA北大核心CSCD

1000-4718

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