中华医学杂志（英文版）2003，Vol.116Issue(4)：633-636,4.
Evaluation of the disc diffusion method with a comparison study for fluconazole susceptibility of Candida strains
Evaluation of the disc diffusion method with a comparison study for fluconazole susceptibility of Candida strains
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作者信息
- 1. Gazi University Faculty of Medicine, Department of Microbiology and Clinical Microbiology, Besevler, 06500, Ankara, Turkey;Gazi University Faculty of Medicine, Department of Microbiology and Clinical Microbiology, Besevler, 06500, Ankara, Turkey;Gazi University Faculty of Medicine, Department of Microbiology and Clinical Microbiology, Besevler, 06500, Ankara, Turkey;Gazi University Faculty of Medicine, Department of Microbiology and Clinical Microbiology, Besevler, 06500, Ankara, Turkey
- 折叠
摘要
Abstract
Objective To performance susceptibility testing of antifungal agents. Due to the increasing number of resistant strains, susceptibility testing of antifungal agents is gaining importance. Methods We compared the results of standard macrotube dilution reference method with two different microdilution methods, as well as the disc diffusion method in order to test the susceptibility of 150 Candida strains to fluconazole. Results Overall correlation between microdilution and macrodilution methods was 86%. It was 91% between the Minimal Inhibitory Concentrations obtained from macrodilution and disc diffusion zone diameters. Conclusion The disc diffusion test was evaluated as a low-cost, reproducible, and efficient way of assessing the in vitro susceptibility of Candida strains to fluconazole.关键词
Antifungal susceptibility tests/macrodilution/microdilution/disc diffusion/fluconazoleKey words
Antifungal susceptibility tests/macrodilution/microdilution/disc diffusion/fluconazole分类
医药卫生引用本文复制引用
..Evaluation of the disc diffusion method with a comparison study for fluconazole susceptibility of Candida strains[J].中华医学杂志（英文版）,2003,116(4):633-636,4.
