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纳米羟基磷灰石在肿瘤领域的应用现状

李妍 石华山 李戈

中国组织工程研究与临床康复2008,Vol.12Issue(32):6393-6396,4.
中国组织工程研究与临床康复2008,Vol.12Issue(32):6393-6396,4.

纳米羟基磷灰石在肿瘤领域的应用现状

Current application of hydroxyapatite nanoparticles in tumor field

李妍 1石华山 2李戈1

作者信息

  • 1. 四川省人民医院儿科,四川省成都市,610072
  • 2. 四川大学华西医院生物治疗国家重点实验室实验肿瘤研究室,四川省成都市,610041
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摘要

Abstract

Hydroxyapatite has already been considered as an excellent medical biomaterial.and nanometer hydroxyapatite possesses special characteristics.Hydroxyapatite nanoparticles can inhibit the growth of a wide range of cancer cells.but have no effect on normal cells.thus it has a better selectivity in the treatment of cancer.The anti-tumor mechanism of nano-hydroxyapatite is relevant on the following factors:role in the cell membrane,affecting DNA synthesis,inducing cell cycle blockage and apoptosis,impacting the activity of telomerase.This study is designed to introduce the specific structure and characterjstics of nano-hydroxyapatite,analyze the research progress of nano-hydroxyapatite in tumor field.and discuss the possibility of nano-hydroxyapatite as a new anti-cancer drug in clinical application.

关键词

纳米羟基磷灰石/肿瘤/生物材料

Key words

Hydroxyapatite and tumor in both Chinese and English

分类

医药卫生

引用本文复制引用

李妍,石华山,李戈..纳米羟基磷灰石在肿瘤领域的应用现状[J].中国组织工程研究与临床康复,2008,12(32):6393-6396,4.

基金项目

Supported by:Scientific Research Program of Sichuan Provinical Health Bureau,No.060128 四川省卫生厅2006年科研项目(060128) (060128)

中国组织工程研究与临床康复

OA北大核心CSCDCSTPCD

2095-4344

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