中国人兽共患病杂志2000，Vol.16Issue(6)：64-66,3.
吡喹酮治疗对日本血吸虫病人抗幽门螺杆菌抗体的影响
EFFECTS OF PRAZIQUANTEL TREATMENT ON HELICOBACTER PYLORI ANTIBODY IN PATIENTS INFECTED SCHISTOSOMA JAPONICUM
摘要
Abstract
Aim To study the effects of praziquantel treatment on the level of Helicobacter pylori(Hp) antibody in patients infected Schistosoma japonicum. Methods The whole cell antigen of Hp was used to detect the Hp IgG antibody in 94 cases of sera from the patients before and after praziquantel treatment. Results The positive Hp infection rate was 73.4％ and 70. 2％ respectively (75.5％ before treatment) after treatment for 3 and 6 months. The level of Hp IgG was 0.71±-0. 30 and 0. 65±0. 21 (0. 80±0. 23 before treatment)respectively. The Hp positive rate and the level of Hp IgG declined with the process of treatment in all age groups,but the Hp IgG level dropped the most quickly in the age group of 0～20. The level and the dropped value of Hp IgG were related to that of Sj31/32 IgG(0. 85 and 0. 65,0. 80 and 0. 50 after treatment for 3 and 6 months). Conclusion The results indicated that the praziquantel treatment can reduce the positive rate and the level of Hp IgG in patients of Schistosoma japonicum. There was a significant correlation between Schistosoma japonicum and Hp infec tion. Schistosoma japonicum might be one of the risk factors of Hp infection.关键词
日本血吸虫/幽门螺杆菌/吡喹酮Key words
Schistosoma japonicum/Helicobacter pylori/Praziquantel treatment分类
医药卫生引用本文复制引用
沈定文,罗金萍,陈喜,彭胜国,王松茂,陈爱山..吡喹酮治疗对日本血吸虫病人抗幽门螺杆菌抗体的影响[J].中国人兽共患病杂志,2000,16(6):64-66,3.基金项目
湖北省教委青年课题资助(97B027) （97B027）
