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Qi盐对大鼠血脂、血黏度及人红细胞变形能力的作用

章蕴毅 赖顺果 李佩芬 李端 黄维蓉 佐藤埝 上田秀夫

中国临床药学杂志2004,Vol.13Issue(2):65-68,4.
中国临床药学杂志2004,Vol.13Issue(2):65-68,4.

Qi盐对大鼠血脂、血黏度及人红细胞变形能力的作用

Effect of Qi salt on the rat serum Hpid, viscosity and human erythrocyte deformation

章蕴毅 1赖顺果 1李佩芬 1李端 1黄维蓉 2佐藤埝 2上田秀夫2

作者信息

  • 1. 复旦大学药学院药理教研室,上海200032
  • 2. 日本Qi盐公司,日本,东京
  • 折叠

摘要

Abstract

AIM:To test the effect of Qi salt on rat experimental hyperlipemia, red blood cell deformability and blood viscosity. METHOD: (1) The Qi salt was given to the rats with hyperlipemia that caused by fat-rich diet for 20 d.The serum HDL-C, LDL-C, total cholesterol and triglyceride were determined. (2) The human red blood cell was incu-bated with different concentration of Qi salt at 37℃ for 1h. Then the red blood cell deformation was measured by methodof micro-pore infiltration. (3) The normal rats were treated with Qi salt for 20 d. The blood was drained from common carotid artery and the viscosity was tested. RESULTS: (1) The serum total cholesterol and LDL-C were lowered by Qidrop of the effect. (3) High dose of Qi salt may increase the blood viscosity but it was less strong than normal salt.CONCLUSION: Qi salt could increase the red blood cell deformation and may lower the serum lipid.

关键词

实验性高脂血症/大鼠/Qi盐/普通盐/红细胞变形能力/血黏度

Key words

experimental hyperlipemia/rat/Qi salt/normal salt/erythrocyte deformation/blood vis-cosity

分类

医药卫生

引用本文复制引用

章蕴毅,赖顺果,李佩芬,李端,黄维蓉,佐藤埝,上田秀夫..Qi盐对大鼠血脂、血黏度及人红细胞变形能力的作用[J].中国临床药学杂志,2004,13(2):65-68,4.

中国临床药学杂志

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1007-4406

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