解剖学杂志2001，Vol.24Issue(1)：65-69,5.
Wistar大鼠不同生理时期乳腺淋巴管的研究
STUDY ON LYMPHATICS OF THE MAMMARY GLAND IN WISTAR RATS UNDER DIFFERENT PHYSIOLOGICAL PERIODS
邵旭建 1辛晓林 2吕雯清 2万军利 2大谷修3
作者信息
- 1. 青岛大学医学院解剖学教研室，青岛266021
- 2. 烟台师范学院生物系
- 3. 日本富山医科药科大学
- 折叠
摘要
Abstract
To qualitatively and quantitatively examine lymphatics of the rnammary gland during different physiological periods in Wistar rats. Methods: The structures analyzed included the area of the endothelia(non-nuclear area), area of the endothelial vesicles, the number and types of open and dose junctions. Twenty Wistar rats were divided into 4 groups: normal, pregnancy on day 7,lactating on day 7, post-weaning on day 7 groups(n ＝ 5). The animals were perfused with 0.9%saline and then with 20 ～ 30 ml India ink through the aorta to distinguish blood vessels from lymphatics The mammary gland tissue was treated with routine LM and TEM procedures. The related research were done by LM, TEM and morphometry. Results: The initial lymphatics of the mammary gland were classified into 3 categories: (1) interlobar lymphatic, (2) interlobular lymphatic and (3) intralobular lymphatic (only found in lactating group). The ratio between the open and the totaljunctions of the lymphatics was 12. 7196 (normal), 2896 (pregnancy on day 7), 37. 6196(lactating on day 7), and 8. 159% (post-weaning on day 7). The area ratio between the endothelial vesicles and the total endothelia in each group was 4.2 96 (normal), 1.9 96 (pregnancy on day 7), 0.996 (lactating on day 7), and 2.796 (post-weaning on day 7). Conclusion: During lactating and pregnancy on day 7, open junctions are the major route for the transport; while in the normal group,the endothelial vesicular transport plays an important role.关键词
淋巴管/乳腺/哺乳期/大鼠Key words
lymphatic/ manmmary gland/ lactating period/ rat分类
医药卫生引用本文复制引用
邵旭建,辛晓林,吕雯清,万军利,大谷修..Wistar大鼠不同生理时期乳腺淋巴管的研究[J].解剖学杂志,2001,24(1):65-69,5.
