中国实用外科杂志2009，Vol.29Issue(8)：665-666,2.
Peutz-Jeghers综合征29例诊治分析
Diagnosis and treatment of Peutz-Jeghers syndrome
杜潇 1赵玉沛 1何小东 1廖泉 1张太平 1郑毅1
作者信息
- 1. 中国医学科学院中国协和医科大学北京协和医院基本外科,北京,100730
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摘要
Abstract
Objective To investigate the clinical feature and treatment of Peutz-Jeghers syndrome(PJS). Methods Twenty-nine cases of PJS admitted in Peking Union Medical College Hospital from 1984 to 2008 were reviewed retrospectively and their clinical characters have been summarized. Results All the 29 patients had polyps in gastrointestinal tract, 27 patients had melanin pigmentation. Definite family history of Peutz-Jeghers syndrome were found in 10 cases (34%). Abdominal pain and hemafecia were the major clinical presentations of this syndrome. 12 cases (41%) complicated with intussusception and 11 cases (38%) with bowel obstructions. Operations were performed in 19 cases, 6 cases underwent polypectomy by endoscopy and 4 patients were given conservative therapy. 26 cases have been proven to be hamartoma of Peutz-Jeghers syndrome by pathologic examination, in which 3 cases had atypical hyperplasia. Conclusion Peutz-Jeghers syndrome has a specific clinical manifestation, and easy to complicated with bowel obstruction, intussusception and digestive tract bleeding. Surgical procedure associating with polypectomy by endoscopy is an appropriate method of treatment. Regular follow-up is indispensable to patients due to the high risk of developing malignant tumors.关键词
Peutz-Jeghers综合征/息肉Key words
Peutz-Jeghers syndrome/ polyps分类
医药卫生引用本文复制引用
杜潇,赵玉沛,何小东,廖泉,张太平,郑毅..Peutz-Jeghers综合征29例诊治分析[J].中国实用外科杂志,2009,29(8):665-666,2.
