国际眼科杂志2008，Vol.8Issue(4)：666-669,4.
镰孢菌属镰刀菌致与接触镜有关的真菌性角膜炎1例
Fusarium sp in severe contact lens related fungal keratitis
Shawarinin Jusoh 1Effat Omar 2Manickam Ravichandran 3Mohtar Ibrahim1
作者信息
- 1. 马来西亚理科大学医学院眼科
- 2. 马来西亚理科大学医学院病理科
- 3. 马来西亚理科大学医学院微生物室
- 折叠
摘要
Abstract
AIM: To report a rare case of severe contact lens related fungal keratitis due to fusarium sp, which not only was successfully treated with therapeutic penetrating keratoplasty but also aided in the confirmation of diagnosis. METHODS:Case report.RESULTS: A 39-year-old private clerk Malay lady who wore extended wear soft contact lens for the past 18 years, presented with acute right eye pain and redness for 10 days duration. Ocular examination showed multiple round feathery paracentral corneal ulcers with presence of minimal hypopyon. Clinical diagnosis of presumed fungal keratitis was made. She was treated with broad spectrum topical antibiotics and antifungal agents after repeated corneal scrapping was negative either for fungi or for the bacteria. However, she developed deterioration of the right eye keratitis. Other topical and systemic antifungal agents were instituted. Unfortunately the right corneal ulcer became further deteriorating. Finally a therapeutic penetrating keratoplasty has done in order to preserve the globe and limit the infection after one and a half months of presentation. The diagnosis and the etiology agent were only confirmed based on histopathological examina-tion and polymerase chain reaction (PCR) from corneal button revealed fusarium sp.CONCLUSION:This case highlights the rare case of fusarium sp as an etiology of severe contact lens related fungal keratitis. This case also illustrates the challenge in managing fungal keratitis. Therapeutic penetrating keratoplasty is the ultimate choice in controlling further infection and perserving the globe.关键词
接触镜/真菌性角膜炎/镰孢菌属镰刀菌Key words
contact lens/fungal keratitis/fusarium sp分类
医药卫生引用本文复制引用
Shawarinin Jusoh,Effat Omar,Manickam Ravichandran,Mohtar Ibrahim..镰孢菌属镰刀菌致与接触镜有关的真菌性角膜炎1例[J].国际眼科杂志,2008,8(4):666-669,4.
