临床医学工程2009，Vol.16Issue(7)：6-7,2.
实时定量逆转录PCR分析D-半乳糖致衰老小鼠胸腺相关基因表达的研究
Thymic-associated Genes Expression Investigation of D-galactose Induced Aging Mouse Model by Real-tlme RT-PCR Method
摘要
Abstract
Objective To establish D-galactose induced aging mouse model and investigate thymic-associated genes expression. Meth-ads Thymic-associated genes expression were measured by real-time RT-PCR method valuing directly thymic microenvironment. Results Compared with control group, thymic-associated genes expression ratios of D-gal group were LM02: 0.94±0.76, FoxnI: 0.45±0.32, IL-7: 0.69±0.7. Concusions In contrast to control group, thymus microenvironment negative gene expressions in D-Gal group have no ob vi ous change, but some necessary gene expressions decrease. So, D-Gal treatment can induce thymus involvation.关键词
D-半乳糖/胸腺/实时定量逆转录PCKKey words
D-galactose/thymus/real-time RT-PCR分类
医药卫生引用本文复制引用
张华华,张国平..实时定量逆转录PCR分析D-半乳糖致衰老小鼠胸腺相关基因表达的研究[J].临床医学工程,2009,16(7):6-7,2.基金项目
广东省湛江市科技计划项目(2007C02010),广东医学院博士启动基金(B2006097). （2007C02010）
