中国现代医学杂志2005，Vol.15Issue(5)：671-672,675,3.
辛伐他汀对不稳定型心绞痛患者的C反应蛋白、白细胞介素-6和纤维蛋白原水平的影响
Effects of simvastatin to levels of CRP, IL-6 and FIB in serum of unstable angina pectoris (UAP) patients
摘要
Abstract
[Objective] To investigate the effects of simvastatin to the levels of C-reaction protein (CRP) and in-terleukin-6(IL-6) and fibrinogen in serum of unstable angina pectoris (UAP) patients. [Methods] 60 UAP inpatientswere randomized. The cases were randomly divided into two groups, simvastatin group and control group. There were30 patients in each group. The patients of control group were administration routine. Besides the simvastatin grouptook 20 mg simvastatin every night for about 8 weeks. [Results] The concentrations of CRP, IL-6 and FIB de-creased obviously in serum of simvastatin group patients after administration. Compared with control group therewere significantly different (P＜.05). There were no correlations with blood lipid decrease by simvastatin. [Conclu-sion] In addition to decrease the concentration of blood lipid, simvastatins have the roles of anti-inflammation andanti-thrombosis. It points out that simvastatin may prevent and cure coronary heart disease (CHD).关键词
辛伐他汀/不稳定型心绞痛/C反应蛋白/白细胞介素-6/纤维蛋白原Key words
simvastatin/UAP/CRP/IL-6/FIB分类
医药卫生引用本文复制引用
陈吉田,芦丽莉,范垂姝,赵康军,荆雪冰,韩海玲..辛伐他汀对不稳定型心绞痛患者的C反应蛋白、白细胞介素-6和纤维蛋白原水平的影响[J].中国现代医学杂志,2005,15(5):671-672,675,3.基金项目
Project of Bei Hua university and provide financial assistance （）
