中国病理生理杂志2001，Vol.17Issue(1)：67-69,3.
冠心病患者血浆神经降压素水平的变化及其临床意义
Changes in plasma neurotension level of patients with coronary heart disease and its clinical significance
刘润梅 1张志寿 2陈素娟 3佟万仁 1李振甲3
作者信息
- 1. 解放军304医院干一科， 北京 100037
- 2. 解放军总医院心内科
- 3. 北京东亚免疫技术研究所，北京 100853
- 折叠
摘要
Abstract
AIM： To investigate the plasma neurotensin(NT) concentration inpatients with coronary heart disease: acute myocardial infarction(AMI),unstable angina(UA),stable angina pectoris(SAP), old myocardial infarction (OMI), and to study the relationship between the plasma NT level and the myocardial ischemia . METHODS: The plasma NT concentration of 30 patients with AMI,32 patients with UA,35 patients with SAP, 31 patients with OMI and 32 normal controls were determined by radioimmunoassay(RIA). RESULTS: The plasma NT level in patients with AMI(24 h),in patients with UA when angina attacked is significantly higher than that of healthy controls. The plasma NT level in patients with SAP, in patients with OMI is not significantly different from that of healthy controls. The NT level of patients with UA when angina attacked is significantly higher than that after 2 weeks treatment (P＜0.01). The NT level of AMI patients rose from early period and reached peak value at 24 h [(72.83±14.34） ng/L] .It began to decline at 48h,and restored to normal level at 72h. CONCLUSION: When acute myocardial ischemia occured in patients with coronary heart disease, the plasma NT level was elevated. This suggests NT may have participated in the pathophysiological course of myocardial ischemia.关键词
冠状动脉疾病/心肌梗塞/心绞痛/神经降压肽分类
医药卫生引用本文复制引用
刘润梅,张志寿,陈素娟,佟万仁,李振甲..冠心病患者血浆神经降压素水平的变化及其临床意义[J].中国病理生理杂志,2001,17(1):67-69,3.
