水生生物学报2006,Vol.30Issue(6):680-683,4.
高效氯氰菊酯对欧洲鲫鱼血清谷丙转氨酶和谷草转氨酶活性的影响
EFFECTIVENESS OF BETA-CYPERMETHRIN ON GLUTAMICPYRUVIC TRANSAMINASE (GPT) AND GLUTAMIC-OXALOACETIC TRANSAMINASE (GOT) ACTIVITIES FROM CRUCIAN CARP ( CARASSIUS AURATUS) SERUM
摘要
Abstract
Beta-cypermethrin is one of the synthetic pyrethroid, which is widely used to control insect pests and is found to be more effective than organphosphates and carbamates. However, it is also reported to be more toxic than organphosphates and carbamates. It has been suggested that synthetic pyrethroids are readily absorbed by the gills of fish even at very low concentrations.Glutamic-pyruvic transaminase (GPT) and glutamic-oxaloacetic transaminase (GOT) exist in the cells of every tissue, particularly in the liver. If the liver is damaged, the enzymes are discharged from the cells into the serum. It increases the GPT and GOT metabolic activities quickly. It is, therefore, proposed that the effects of toxicants on serum GPT and GOT could be used as indexes in toxicological assessments. In this experiment, the effectiveness of beta-cypermethrin on the acute toxicity and on serum GPT and GOT concentration of crucian carp was studied. The LC50 of beta-cypermethrin for crucian carp was 11.4μg/L. The crucian carp serum was treated against beta-cypermethrin levels of 0.114μg/L, 0.57μg/L and 1.14μg/L for exposure times of 0d, 5d,10d, 15d and 20d, at all concentrations. The results show that when the beta-cypermethrin concentration increases and the exposure time is prolonged, the GPT and GOT activities of serum increased also. The results proved that beta-cypermethrin could cause great damage to crucian carp and its biochemical functions.关键词
Beta- cypermethrin/Acute toxicity/GPT/GOTKey words
Beta- cypermethrin/Acute toxicity/GPT/GOT分类
生物科学引用本文复制引用
WANG Yuan,XIONG Li,TANG Hong-Feng,SHENG Xiu-Mei,LOU An ,LI Jin..高效氯氰菊酯对欧洲鲫鱼血清谷丙转氨酶和谷草转氨酶活性的影响[J].水生生物学报,2006,30(6):680-683,4.基金项目
the National Basic Research Program (973 Program) (No. 2001CCB00700) (973 Program)
Wuhan Chenguang Scientific Program (No. 2002500103) (No. 2002500103)