国际医药卫生导报2009，Vol.15Issue(9)：68-70,3.DOI:10.3760/cma.j.issn.1007-1245.2009.09.028
62例骨髓移植患者应用抗真菌药物预防的临床疗效分析
Analysis of clinical effect of antifungal agents in 62 cases of bone marrow transplant patients
郑润辉 1王春燕 1谭获 1黄振倩 1刘丹1
作者信息
- 1. 510230,广州医学院第一附属医院肿瘤血液中心
- 折叠
摘要
Abstract
Objective To analyze the clinical efficacy of antifungal drug treatment in patients after bone marrow transplantation. Methods Analysis retrospectively the fungal infection rate and the application of antifungal agents in 62 cases of bone marrow transplant patients in the past 5 years in our center. Group A (38 cases) was no fungal infections before bone marrow transplantation. Group B (24 case) was of clinical diagnosis of fungal infection which is stable pre-transplant. All 62 patients accepted a variety of antifungal agents treatment in the transplant process. Results Fungal infection rate in total 62 cases was 12.9%. Of them the rate of prevent fungal infection by antifungal agents orally in group was 5.26% and 60% in group by oral drugs. The rate of broad-spectrum antifungal drug injections to prevent infection was 0%, and the rate of oral plus injection to prevent the total infection was 25%. Conclusion The incidence of fungi was high in bone marrow transplantation. The choice of different antimicrobial spectrum and intensity of antimicrobial drugs were based on patients with previous fungal infections.关键词
骨髓移植/真菌感染Key words
Bone marrow transplantation/ Fungal infections分类
医药卫生引用本文复制引用
郑润辉,王春燕,谭获,黄振倩,刘丹..62例骨髓移植患者应用抗真菌药物预防的临床疗效分析[J].国际医药卫生导报,2009,15(9):68-70,3.
