伤残医学杂志2001，Vol.9Issue(1)：6-9,4.
大鼠延髓后角NKR样阳性神经元与伤害性信息感受神经元关系的光镜观察
Observation of the Relationship of Neurokinin B Receptor Immunoreactivity and Nociception Sensory Neurons in Rat Medullas Oblongata
李翼飞 1王春杨 1王红 2邵大伟3
作者信息
- 1. 哈尔滨医科大学附属第二医院泌尿外
- 2. 第四军医大学基础部组织学与胚胎学教研室
- 3. 哈尔滨医科大学
- 折叠
摘要
Abstract
Objective: To examine the distributions and relationships between neurokinin B receptor like (NKR-Li) and FOS like (FOS-Li) immunoreactivity neurons qualitatively. Methods:Immunofluoresence histochemical double-staining technique was used and colocalization of NKR was investigated through serial adjacent section methods. Bandeiraea Simplicifolia Isolectin-B4 (BSI-B4)labelled primary afferent C fibers and terminals in the superficial laminae of the trigeminal subnuleus caudalis (Vc). Results: The immunostaining showed that intense FOS-Li and moderate NKR-Li neurons in the superficial laminae of medullae oblongata dorsal horn and their mainly part of the distribution were overlapped. Parts of the distribution of NKR-Li were obviously overlapped by the BSI-B4 labeled primary afferent C fibers and terminals. Additionally, few typical double-labeled neurons of KR-Li and FOS-Li were found. Conclusion: The present results suggested that NKR immunoreactivity neurons might be involved in the modulation of the primary afferent nociceptive stimulation information. But NKR-Li neurons were not stained for FOS, they may be unspecial nociception sensory internal neurons.关键词
大鼠延髓后角NKRc-fos荧光显微镜分类
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李翼飞,王春杨,王红,邵大伟..大鼠延髓后角NKR样阳性神经元与伤害性信息感受神经元关系的光镜观察[J].伤残医学杂志,2001,9(1):6-9,4.
