首页|期刊导航|东华大学学报（英文版）|Surface Modification of Anionic Polyurethane with Silk Fibroin Peptide and Its Effects on the Culture of Fibroblasts
东华大学学报（英文版）2007，Vol.24Issue(6)：695-699,706,6.
Surface Modification of Anionic Polyurethane with Silk Fibroin Peptide and Its Effects on the Culture of Fibroblasts
Surface Modification of Anionic Polyurethane with Silk Fibroin Peptide and Its Effects on the Culture of Fibroblasts
摘要
Abstract
The surface modification of the anionicpolyurethane(APU) film was carried out by immersing it insilk fibroin peptide(SFP) solution for 12 h and then treatingwith low temperature plasma glow discharge. The physicalproperties and moisture permeability of modified films wereexamined. The results showed that SFP-modified APU filmshad better moisture permeability than oleophilicpolyurethane, as well as modified APU films kept goodflexibility. Modified APU films could overcome rigid andbrittle weaks of silk fibroin films. The morphology of SFPon the APU film was corpuscular aggregations. The water-contact angle measurement indicated that the change ofhydrophilicity and the element chemical analysis suggestedthat the SFP-modified film surface was enriched withnitrogen atoms. The biocompatibility of APU films may beimproved due to the change of surface compooents. Cellviability and proliferation of rat embryo dermal fibroblastsseeded on control films, APU films and SFP-modified APUfilms were evaluated by MTT assay and viable cell counts,respectively. The results indicated that the APU filmmodified by SFP protein showed the proliferation offibroblasts on the film, and that the compound interface hadgood stability in the air. Results also showed thatpresoaking treatment for APU films was effective toaccomplish the goal of surface modification.关键词
anionic polyurethane/ silk fibroin peptide/modification/ fibroblastKey words
anionic polyurethane/ silk fibroin peptide/modification/ fibroblast分类
化学化工引用本文复制引用
SUN Dong-hao,WU Zheng-yu,LI Ming-zhong,BAI Lun,SHENG Wei-hua..Surface Modification of Anionic Polyurethane with Silk Fibroin Peptide and Its Effects on the Culture of Fibroblasts[J].东华大学学报（英文版）,2007,24(6):695-699,706,6.基金项目
Supported by the National Basic Research 973 Program of China (No. 2005CB623906) （No. 2005CB623906）
