中国科学院研究生院学报2003，Vol.20Issue(1)：7-12,6.
人体血浆中Tb(Ⅲ)物种的计算机模拟研究
Computer Simulation of Tb( Ⅲ )Speciation in Human Blood Plasma
摘要
Abstract
A multi-phase model of human blood plasma was developed and the Tb( Ⅲ) specia-tion in this system was studied. The results show that the speciation of Tb( Ⅲ ) depends onthe concentration of Tb( Ⅲ ). When the concentration of Tb( Ⅲ ) is below 4. 000 × 10-8 mol/L,most of Tb ( Ⅲ ) exists as soluble species while the concentration of Tb ( Ⅲ ) is in between4. 000× 10-8 mol/L and 1. 667 × 10-2 mol/L, precipitates (TbPO4 and Tb2 (CO3)3) are thedominant species of Tb(Ⅲ). Among soluble Tb(Ⅲ) species, Tb( Ⅲ) is mostly bound to thetransferrin to form [Tb(Tf)] when the concentration of soluble Tb(Ⅲ) is below 1.0 × 10 4mol/L. The concentration of soluble Tb(Ⅲ) reaches 1.0 × 10-4mol/L, thus available trans-ferrin is exceeded, and soluble Tb(Ⅲ) ions mainly distribute in [Tb(HSA)], [Tb2 (Tf)],[Tb(Ox)] and [Tb(Cit)] etc.关键词
计算机模拟,物种,人体血浆,Tb(Ⅲ)Key words
computer simulation, speciation, human blood plasma, terbium( Ⅲ)分类
生物科学引用本文复制引用
卢兴,张海元,王进平,王悦,杨魁跃,牛春吉,倪嘉缵..人体血浆中Tb(Ⅲ)物种的计算机模拟研究[J].中国科学院研究生院学报,2003,20(1):7-12,6.基金项目
supported by National Natural Acience Foundation of China(29890280, 29971029) （29890280, 29971029）
