中国组织工程研究与临床康复2008，Vol.12Issue(37)：7398-7400,3.
雌激素受体与绝经后骨质疏松症
Relationship between estrogen receptor and postmenopausal osteoporosis
白旭华1
作者信息
- 1. 内蒙古民族大学医学院,内蒙古自治区通辽市,028041
- 折叠
摘要
Abstract
Both Pubmed database and China Academic Journals Full-text Database were retrieved to search the articles about the relationship between estrogen receptor (ER) and postmenopausal osteoporosis. There are two subtypes of ER widely distributed in the human body, ER α and ER β. According to the bound receptor subtypes, estrogen activates selectively intracellular signaling pathway, and expresses various biological activities. The regulation of estrogen on bone resorption is effected through being mediated by certain cytokines or directly functioning on osteoclasts. In recent years, the specific effect of selective ER modulator on two different receptor subtypes has become the hot topic for treatment of osteoporosis.关键词
骨质疏松症/雌激素/雌激素受体/组织构建分类
医药卫生引用本文复制引用
白旭华..雌激素受体与绝经后骨质疏松症[J].中国组织工程研究与临床康复,2008,12(37):7398-7400,3.
