临床神经病学杂志2001，Vol.14Issue(2)：74-75,2.
神经元特异性烯醇酶与急性脑梗死
Neuron-specific enolase and acute cerebral infarction
王义刚 1邢永前 1郑华 1梁学标 1黄迪南2
作者信息
- 1. 广东医学院附属医院神经内科
- 2. 广东医学院生化教研室
- 折叠
摘要
Abstract
Objective To explore the change and clinical significance of serum neuron-specific enolase (NSE) in the patients with acute cerebral infarction.Methods Blood samples(serum NSE levels) of 69 patients with cerebral infarction were determined by ELISA in the first 3 days,and 35 patients of them were determined again 2 weeks the onset.Results NSE serum levels of patients were significantly higher in the first 3 days than in 2 weeks after the onset and the controls(P<0.001),there was a positive correlation between serum NSE levels and the volume of infraction, neurological deficit scores(P<0.001),and it was negative correlation with disorder of consciousness(P<0.001),the higher serum NSE levels indicated the worse clinical curative effect(P<0.001).Conclusion Serum NSE levels were increased in the early stage of cerebral infarction, and there was a close relationship between NSE serum levels and clinical features.关键词
脑梗死/神经元特异性烯醇酶分类
医药卫生引用本文复制引用
王义刚,邢永前,郑华,梁学标,黄迪南..神经元特异性烯醇酶与急性脑梗死[J].临床神经病学杂志,2001,14(2):74-75,2.
