河南中医2009，Vol.29Issue(8)：756-758,3.
红藤对小鼠的免疫抑制效应
Immunosuppressive Effect of Caulis Sargentodoxae on Mice
摘要
Abstract
Objective: To probe the immunosuppressive effect of caulis sargentodoxae on mice. Methods: Consistent gastric perfusion of canlis sargentodoxae 25 rag/100 ml were givern to mice( 18 ～ 22 g) for 7days to detect the earban clearance, antibodyproducing cells, lymphocyte a-naphtyl acetate esterase, transformation of spleen lymphocyte, delayed-type hypersensitivity. Results :Compared with control group, canlis sargentodoxae decoction inhibited the activity of mononuclear-macrophage, and decreased the antibody-secreted IgM content of antibody producing cells, inhibited the number of peripheral blood T lymphocyte, decreased the trasformation rate of spleen lymphocyte, decreased the weight difference of DNCB-sensitized mice ears. Compared with those of control group, all indexes of experiment groups had significantly statistic difference(P＜0.01). Conclusion: Caulis sargentodoxae has significant inhibiting effects on the immanofunction of cells and body fluids, which provides a sci-entific basis for the development of Chinese medicinal immunosuppressant.关键词
红藤/免疫抑制/单核-巨噬细胞/淋巴细胞/IgM/小鼠Key words
caulis sargentodoxae/immunosuppression/mononuclear-macrophage/lymphocyte/IgM/mice分类
医药卫生引用本文复制引用
王红梅,马素好..红藤对小鼠的免疫抑制效应[J].河南中医,2009,29(8):756-758,3.基金项目
河南省科技攻关项目(编号:0524420040) （编号:0524420040）
