中国现代医学杂志2003,Vol.13Issue(20):75-77,81,4.
卡托普利对控制性降压中硝普钠用量的影响
EFFECTS OF CAPTOPRIL ON THE DOSE REQUIRMENT OF SODIUM NITROPRUSSIDE IN CONTROLLED HYPOTENSION
梁幸甜 1杨承祥1
作者信息
- 1. 广东省佛山市第一人民医院麻醉科,528000
- 折叠
摘要
Abstract
Objective:To study the feasibility of applying captopril combined with sodium nitroprusside (SNP) in controlled hypotension.Methods:Patients in test group pretreated orally with captopril, 1 mg/kg 1 hour before induction of anesthesia, received a similar anesthetic technique with those in control group. Both groups maintained SBP at (85±10)mmHg and data such as SBP, DBP, MAP, PR, HR, ECG, SPO2, PETCO2 and the dose requirement of SNP were observed. The data were treated by statistical analysis at the end.Results:Patients in test group required less SNP [(1.3±0.6)μg/kg/h] significantly than those in control group[(2.6±0.9)μg/kg/h].SNP has obviously relieved both the reflectivity tachycardia and the rebound hypertension in test group.Conclusions:Captopril, given orally before surgery, combined with SNP, given through infusion pump during surgery,is proved to be safe and valid in controlled hypotension.关键词
控制性降压/卡托普利/硝普钠Key words
Controlled Hypotension/Captopril/Sodium Nitroprusside分类
医药卫生引用本文复制引用
梁幸甜,杨承祥..卡托普利对控制性降压中硝普钠用量的影响[J].中国现代医学杂志,2003,13(20):75-77,81,4.