吉首大学学报（自然科学版）2008，Vol.29Issue(4)：75-82,8.
原儿茶酸分子印迹聚合物的色谱识别性能
Analogue Recognition and Chromatographic Behaviors of Molecularly Imprinted Polymer for Protocatechuic Acid
摘要
Abstract
A non-covalent imprinting approach was applied to synthesize protocatechuic acid (3,4-dihydroxybenzoicacid) imprinted polymers (MIPs) in the polar tetrahydrofuran by using methacrylic acid as functional monomer. Byequilibrium adsorption experiments and high performance liquid chromatography (HPLC), the rebinding properties ofthe MIPs to protocatechuic acid (template) and its analogues were evaluated. It was found that the MIPs exhibited highadsorption capability and selectivity for the template and two kinds of absorption sites in the polymer were detected byScatchard curve analysis. The eluents and the mobile phase flow rate had an important influence on the retention of theanalytes on the MIPs column. All of the results showed that the stronger affinity of the MIPs to the template than its an-alogues resulted from the size and shape recognition in the MIPs network based on hydrogen bonding interaction.关键词
分子印迹聚合物/原儿茶酸/平衡吸附/高效液相色谱Key words
molecularly imprinted polymer/protocatechuic acid/equilihrium adsorption/HPLC分类
化学化工引用本文复制引用
李亚男,李辉,石慧,张朝晖,胡文斌,李志平,欧阳玉祝..原儿茶酸分子印迹聚合物的色谱识别性能[J].吉首大学学报（自然科学版）,2008,29(4):75-82,8.基金项目
Science Research Foundation of Administration of Education of Hunan Province （）
