中华医学杂志(英文版)2002,Vol.115Issue(5):776-778,3.
短肠综合征的康复治疗
Rehabilitation therapy for short bowel syndrome
朱维铭 1李宁 1任建安 1顾军 1姜军 1黎介寿1
作者信息
- 1. 南京军区南京总医院,南京大学医学院临床学院,南京,210002
- 折叠
摘要
Abstract
Objective To investigate the effect of rehabilitation therapy for short bowel syndrome on patient nutritional status and intestinal adaptation.Methods The rehabilitation therapy included enteral or parenteral nutrition, glutamine, recombinant human growth hormone and rehabilitative diet. From January 1997 to July 2000, twenty-seven patients with short bowel syndrome received the treatme nt. The average age of the patients was 38.5±19.3 years, and the length of r esidual small intestine ranged from 15 to 80 cm, with an average of 46.8±23.4 cm. The ileocecal valve was preserved in 14 cases, and the average time betwee n the onset of short bowel syndrome and the rehabilitation therapy was 86±105 d ays.Results After the treatment, nutritional status of the patients improved markedly, and i ntestinal absorptive capacity improved. Eight patients were followed up for mor e than 2 years, among whom 4 (50%) were weaned from total parenteral nutrition. Thirteen patients were followed up for more than 1 year, and 10 patients (76.9 %) were weaned from total parenteral nutrition.Conclusions Rehabilitation therapy for short bowel syndrome can improve patient nutritional status effectively and promote intestinal adaptation, providing a new hope for t hese patients. The therapeutic effects are related to the length of the residua l small intestine, patient's age and duration between massive intestinal resecti on and start of the treatment. Early initiation of rehabilitation therapy promo tes intestinal adaptation and increases patient's ability to wean from total par enteral nutrition.关键词
短肠综合征/营养/康复/谷氨酰胺/生长激素Key words
nutrition/glutamine/rehabilitation/short bowel syndrome/somatotropins recombinant分类
医药卫生引用本文复制引用
朱维铭,李宁,任建安,顾军,姜军,黎介寿..短肠综合征的康复治疗[J].中华医学杂志(英文版),2002,115(5):776-778,3.