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A review of Leishmaniasis in Eastern Africa

Peter K. Ngure Albert Kimutai Zipporah W. Ng'ang'a Geoffrey Rukunga Willy K. Tonui

南京医科大学学报(英文版)2009,Vol.23Issue(2):79-86,8.
南京医科大学学报(英文版)2009,Vol.23Issue(2):79-86,8.

A review of Leishmaniasis in Eastern Africa

A review of Leishmaniasis in Eastern Africa

Peter K. Ngure 1Albert Kimutai 2Zipporah W. Ng'ang'a 3Geoffrey Rukunga 4Willy K. Tonui4

作者信息

  • 1. Science Department, Daystar University, Nairobi 44400-00100, Kenya
  • 2. Kenyatta University, Nairobi 43844, Kenya
  • 3. Jomo Kenyatta University of Agriculture and Technology, Nairobi 62000, Kenya
  • 4. Kenya Medical Research Institute, Nairobi 54840,Kenya
  • 折叠

摘要

Abstract

The review presents the epidemiology of leishmaniasis in the Eastern Africa region. We searched PUB MED and MEDLINE with several key words-namely,"leishmaniasis";"cutaneous"," diffuse cutaneous"," mucosal", and "visceral leishmaniasis";"kala azar" and "post kala azar dermal leishmaniasis"-for recont clinical and basic science articles related to leishmaniasis in countries in the Eastern Africa region. Poverty, wars, conflicts and migration have significantly aggravated leishmaniases in Eastern Africa. Of particular concern is the increasing incidence of Leishmania-HIV co-infection in Ethiopia where 20--40% of the persons affected by visceral leishmaniasis are HIV-co-infected. Sudan has the highest prevalence rate of post kala-azar dermal leishmaniasis(PKDL) in the world, a skin complication of visceral leishmaniasis(VL) that mainly afflicts children below age ten. In view of its spread to previously non-endemic areas and an increase in imported cases, leishmaniasis in Eastern Africa should be considered a health emergency.

关键词

Leishmaniasis/cutaneous/visceral/Eastern Africa

Key words

Leishmaniasis/cutaneous/visceral/Eastern Africa

分类

医药卫生

引用本文复制引用

Peter K. Ngure,Albert Kimutai,Zipporah W. Ng'ang'a,Geoffrey Rukunga,Willy K. Tonui..A review of Leishmaniasis in Eastern Africa[J].南京医科大学学报(英文版),2009,23(2):79-86,8.

南京医科大学学报(英文版)

1674-8301

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