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宫颈鳞癌PCNA表达及DNA倍体与癌转移关系的研究

马俊华 熊艳 汪必成 熊永炎 林宜先

医学新知杂志2001,Vol.11Issue(2):80-81,2.
医学新知杂志2001,Vol.11Issue(2):80-81,2.

宫颈鳞癌PCNA表达及DNA倍体与癌转移关系的研究

A Study on Relationship of PCNA Expression and DNA Ploidy Detection with the Metastasis of Cervical Squamous Cell Carcinoma

马俊华 1熊艳 2汪必成 3熊永炎 3林宜先3

作者信息

  • 1. 武汉军工总医院妇产科 武汉 430033
  • 2. 武汉大学中南医院肿瘤科 武汉 430071
  • 3. 武汉大学中南医院病理科 武汉 430071
  • 折叠

摘要

Abstract

To explore the correlation between the tumor prolifer ative activity and the metastasis of cervical squamous cell carcinoma, the expre ssion of Proliferating Cell Nuclear Antigen(PCNA) and DNA Content Index (DI) wer e investigated using SP immunohistochemical staining and image analysis in 65 ca ses. Result:The expression of PCNA and DNA content were correlated with tumor differentiation and metastasis; as well as there was a striking association betw een PCNA and DI.These indicated that higer proliferative activity always means l ower differentiation and higer metastasive potention of the cervical squamous ce ll carcinoma.

关键词

宫颈鳞状细胞癌/转移/PCNA/DNA含量

Key words

Cervical squamous cell carcinoma/Metastasis/PCNA/DI

分类

医药卫生

引用本文复制引用

马俊华,熊艳,汪必成,熊永炎,林宜先..宫颈鳞癌PCNA表达及DNA倍体与癌转移关系的研究[J].医学新知杂志,2001,11(2):80-81,2.

医学新知杂志

1004-5511

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