华西医科大学学报2001，Vol.32Issue(1)：80-82,3.
Enalapril对实验性糖尿病大鼠肾脏的保护作用机理研究
The Mechanism of Protective Effects of Enalapril on Experimental Diabetic Nephropathy of Rats
摘要
Abstract
Objective To elucidate the mechanisms of renoprot ective effectsof ACEI on diabetic animals and patients. Methods STZ-induced diabetic rats were treated with Enalapril and the levels of urine protein, TGF-β and AGEs in renal tissue were measured and compared. R esults The results of TGF-β quantitation and AGE fluorescence of Enal april treatment group rats were the same as those of diabetic control rats. Conclusion Suppression of TGF-β overexpression or AGEs accumulati on was not implicated in the mechanisms of renoprotective effects of ACEI.关键词
糖尿病肾病 Enalapril 转化生长因子-β 糖基化终末产 物 血管紧张素转化酶抑制剂分类
医药卫生引用本文复制引用
傅静奕,田浩明,梁荩忠..Enalapril对实验性糖尿病大鼠肾脏的保护作用机理研究[J].华西医科大学学报,2001,32(1):80-82,3.
