中国中西医结合杂志2001，Vol.21Issue(2)：85-89,5.
感染性多脏器功能不全综合征中西医结合诊治的研究
Study on Diɑgnosis ɑnd Treɑtment of Infectious Multiple Organ Dysfunction Syndrome by Integrated Traditional Chinese and Western Medicine
张淑文 1任爱民 1张丽霞 1王红 1毕铭华 1李昂 1次秀丽 1王彦 1齐文杰 1王宝恩1
作者信息
摘要
Abstract
Objective: To explore the diagnostic and therapeutic approach ofintegrated traditional Chinese and western medicine (TCM-WM) on infectious multiple organ dysfunction syndrome/multiple system and organ failure (MODS/MSOF) for elevating the successful rate of rescuing the patients. Methods: Diagnosis with western medicine and Syndrome Differentiation of TCM in 225 in-patients of acute infectious disease complicated with MODS/MSOF were conducted, and TCM treatment, based on western medical comprehensive treatment, was given to observe the effect and explore the mechanism of the TCM-WM therapy. Results: Up to the end of 1998, 161 cases of the 225 cases were successfully cured and 64 died, the mortality being 28.4%. Among them, 58 out of 140 cases of MSOF died, the mortality was accounted for 41.4%. In 106 cases conformed to the diagnostic criteria of MSOF proposed by Professor Knaus WA, USA, 52 cases were cured successfully and 54 died, the mortality being 50.9%. Conclusion: TCM-WM treatment could elevate the therapeutic effect in treating MODS, the mechanism might be through improving the hemodynamic and hemorrheologic condition of patients to relieve nail-fold microcirculation disorder; influencing the levels of cytokine and inflammatory mediator, so as to alleviate the systemic inflammatory reaction, it might also abate the inhibited condition of gastro-intestinal motility, alleviate the intestinal flora imbalance, prevent intestinal bacteria and endotoxin malposition, and protect cells from peroxidation.关键词
感染/多脏器功能不全综合征/多脏衰/内毒素/中医证型分类
医药卫生引用本文复制引用
张淑文,任爱民,张丽霞,王红,毕铭华,李昂,次秀丽,王彦,齐文杰,王宝恩..感染性多脏器功能不全综合征中西医结合诊治的研究[J].中国中西医结合杂志,2001,21(2):85-89,5.
