北京师范大学学报(自然科学版)2001,Vol.37Issue(1):87-91,5.
荧光法研究氟罗沙星与牛血清白蛋白的相互作用
STUDY ON THE INTERACTION OF BOVINE SERUM ALBUMIN AND FLEROXACIN BY FLUORESCENCE METHOD
摘要
Abstract
A fluorescence method is used to study the fluorescence quenchingof bovine serum albumin by its interaction with fleroxacin. The interaction association constants of bovine serum albumin and fleroxacin are determined from a double reciprocal Lineweaver-Burk plot. According to the Fster dipole-dipole energy transfer, the distance to be measured between the fleroxacin and tryptophane is 4.37 nm. From thermodynamical coordination it can be judged that the binding power between fleroxacin and bovine serum albumin is static electric power.关键词
荧光猝灭/牛血清白蛋白/氟罗沙星/能量传递分类
化学化工引用本文复制引用
聂丽华,赵慧春,王学斌,王旭..荧光法研究氟罗沙星与牛血清白蛋白的相互作用[J].北京师范大学学报(自然科学版),2001,37(1):87-91,5.基金项目
国家自然科学基金资助项目(29971005) (29971005)