基础医学与临床2001，Vol.21Issue(1)：88-90,3.
用快速心室起搏研制充血性心力衰竭兔模型
A congestive heart failure model induced by ventricular rapid pacing in rabbit
戚本玲 1曹林生 2曾秋棠 2李裕舒 2吴桂芳 2毛奕2
作者信息
- 1. 同济医科大学附属协和医院 心血管病研究所，武汉 430022
- 2. 同济医科大学附属协和医院 心血管病研究所,
- 折叠
摘要
Abstract
The study was to produce a CHF model by ventricular chronic rapid pacing in rabbits. The ventricules of 7 rabbits (P group) were paced by external pacemakers for 3 weeks, 9 sham-operated rabbits were served as control group (C group). After pacing for 3 weeks, Cardiac size, left ventricular end diastolic pressure and central venous pressure were increased in paced rabbit than in the control rabbits. In P group, left ventricular ejection fraction, left ventricular shorten fraction, cardiac output, arterial mean pressure and±dp/dt were lower in paced rabbits than that in the control rabbits. CHF can be produced in rabbits by chronic rapid ventricular pacing.关键词
心室起搏/充血性心力衰竭/兔分类
医药卫生引用本文复制引用
戚本玲,曹林生,曾秋棠,李裕舒,吴桂芳,毛奕..用快速心室起搏研制充血性心力衰竭兔模型[J].基础医学与临床,2001,21(1):88-90,3.
