肿瘤防治研究2001，Vol.28Issue(2)：89-91,3.
癌性体液细胞中端粒酶活性的研究及意义
Study on Telomerase Activity in Exfoliated Cells from Humoral Specimens and its Significance
摘要
Abstract
Objective To study telomerase activity of exfoliated cells inhumoral specimens from patients with malignant neoplasms.Methods Polymerase chain reaction-Enzyme linked immunosorbented assay (PCR-ELISA)was applied to detect telomerase activity in pleural effusion,ascites,urine from patients with malignant neoplasms.Results Telomerase activity was detected in 33 of 54 pleural effusion and ascite cells from patients with malignant neoplasms in humoral specimens,the overall positive rate is 61.11%.Telomerase positive rate is 70% in pleural effusion cells from patient with lung cancer,83.64% in exfoliated cells in urine from patients with bladder cancer,while,positive rate of cytological examination is 53.33%(16/30) and 52.72%(29/55).Conclusion The results suggested that detection of telomerase activity of humores cells would be helpful for the diagnosis of patients with malignant neoplasms.关键词
端粒酶/体液/检测/肿瘤分类
医药卫生引用本文复制引用
祝怀平,戴海明,何义富,凌斌,吴奎,丁敏..癌性体液细胞中端粒酶活性的研究及意义[J].肿瘤防治研究,2001,28(2):89-91,3.基金项目
安徽省卫生厅基金资助项目(A95-1998-25) （A95-1998-25）
