中华医学杂志（英文版）2001，Vol.114Issue(9)：906-908,3.
甲状腺功能减退患者心率变异及对治疗的反应
Heart rate variability and its response to thyroxine replacement therapy in patients with hypothyroidism
邢惠莉 1陈寒蓓 1王一尘 1沈迎 2沈卫峰3
作者信息
- 1. 上海第二医科大学附属新华医院内分泌科
- 2. 上海第二军医大学
- 3. 上海第二医科大学附属瑞金医院心脏科
- 折叠
摘要
Abstract
Objective To analyze heart rate variability (HRV)and its changes with thyroxine treatment in patients with hypothyroidism.
Methods HRV was analyzed using 24-hour electrocardiographic recording in 38 patients with hypothyroidism and 21 normal controls. The changes in HRV were evaluated for the 18 hypothyroid patients after 3 months of thyroxine therapy.
Results The time domain measurements of HRV in hypothyroid patients were much lower than those in the control group. As to HRV frequency domain, the high frequency power was significantly higher, but the ratio of low frequency power to frequency power for hypothyroid patients was lower than in the controls. These abnormal changes of HRV measurements in hypothyroid patients were improved after treatment with thyroxine and were associated with recovery of serum concentrations of FT3 and FT4.
Conclusions Patients with hypothyroidism often have autonomic neuropathies with a higher level of vagal tone. These abnormalities could be partly improved by thyoxine therapy.关键词
心率变异性/甲状腺功能减退/自主神经功能分类
医药卫生引用本文复制引用
邢惠莉,陈寒蓓,王一尘,沈迎,沈卫峰..甲状腺功能减退患者心率变异及对治疗的反应[J].中华医学杂志（英文版）,2001,114(9):906-908,3.
