国际眼科杂志2007，Vol.7Issue(4)：906-908,3.
注入式义眼座技术的初步报告
Experimental study of injectable intraocular prosthesis in rabbits-Preliminary report
刘瑶 1屠颖 2丁传凤 1王爱莲 1王峻岭1
作者信息
- 1. 213000,中国江苏省常熟市,苏州大学附属第三医院眼科
- 2. 中国江苏省江阴市人民医院眼科
- 折叠
摘要
Abstract
· AIM: To search an easy and simple way for intraocular implantation after the eye evisceration.· METHODS: Fifteen healthy New Zealand rabbits were divided into 5 groups according to the sacrifice time, and each group included 3 rabbits; the left eye received the injection of polymethyl methacrylate (PMMA) bone cement (2g per mL), while the right eye served as control. Under general anesthetia, a 3mm incision was made on the sclera,and the eye contents and pigment tissues were extruded out with fingers. Then, PMMA bone cement (2g per ml) was injected through the scleral incision. Both the operated eye and control eye of the rabbits were enucleated and weighed,The reaction of the operated eye (macroscopically and histopathologically) was noted at frequent interval. The obtained data were then analyzed with ANOVA (SPSS11.5).· RESULTS: There was swelling of eyelids and conjunctiva at the early time after the injection, but no significant difference between the weight of the left and right eyes was noted,Histopathologic examination showed scleral and other tissues necrosis at early period, and then the tissues reaction turned into a great deal of cell proliferation and finally into extensive fibro-connective tissues. Three months after the operation,neovascularization was observed in the cornea of the operated eyes. Histopathologic examination showed formation of fibro-membrane around the intraocular implant,and disappearance of the inflammation.· CONCLUSION: The method of injecting PMMA bone cement (2g per ml) to form an intraocular implant is quite simple and economical; this method is also easy to use clinically.关键词
注射/义眼座/聚甲基丙烯酸甲酯骨水泥Key words
injectable intraocular prosthesis/ PMMA bone cement分类
医药卫生引用本文复制引用
刘瑶,屠颖,丁传凤,王爱莲,王峻岭..注入式义眼座技术的初步报告[J].国际眼科杂志,2007,7(4):906-908,3.
