中华医学杂志(英文版)2007,Vol.120Issue(10):922-928,7.
Pharmacological action and mechanisms of ginkgolide B
Pharmacological action and mechanisms of ginkgolide B
摘要
Abstract
Objective To review the recent research progress in pharmacological actions and mechanisms of ginkgolide B.Data sources Information included in this article was identified by searching of PUBMED (1987-2006) online resources using the key terms "ginkgolide B", "platelet activating factor", and "pharmacological".Study selection Mainly original milestone articles and critical reviews written by major pioneer investigators of the field were selected.Results The key issues related to the pharmacological actions and mechanisms of ginkgolide B were summarized. The ginkgolide B possesses a number of beneficial effects such as anti-inflammatory, anti-allergic, antioxidant, and neuroprotective effects. Meantime, their mechaniams were discussed.Conclusions The Ginkgolide B is the most potent antagonist of platelet activating factor (PAF) and exhibits therapeutic action in a variety of diseases mainly by the PAF receptor.关键词
ginkgolide B/platelet activating factor/pharmacological actionsKey words
ginkgolide B/platelet activating factor/pharmacological actions分类
医药卫生引用本文复制引用
XIA Shi-hai,FANG Dian-chun..Pharmacological action and mechanisms of ginkgolide B[J].中华医学杂志(英文版),2007,120(10):922-928,7.基金项目
This study was supported by the National Natural Science Foundation of China (No. 30300465). (No. 30300465)