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胡芦巴总皂苷对脑缺血保护作用

李琳琳 冉新建 毛新民 王雪飞 张杰 王飞

中国药理学通报2001,Vol.17Issue(1):92-94,3.
中国药理学通报2001,Vol.17Issue(1):92-94,3.

胡芦巴总皂苷对脑缺血保护作用

Protective effects of trigonella foenum graecum L. on acute cerebral ischemia

李琳琳 1冉新建 1毛新民 1王雪飞 1张杰 1王飞1

作者信息

  • 1. 新疆医科大学基础部药理学教研室室,
  • 折叠

摘要

Abstract

AIM To study the protective effects of trigonella foenum graecum(TFGs) on acute cerebral ischemia. METHODS Acute incomplete ischemia was induced by ligaturing bilateral carotid arterise and cutting heads in mice, the survival time and asthmatic time were observed; the coagulation timewas measured by sheet glass method,and the blood viscosity was also assayed; the platelet aggregation induced by collagen were studied by turbdimetry in vitro. RESULTS TFGs prolonged survival time, coagulation time and asthmatic time significantly and inhibited platelet aggregation ratio in rabbit,and decreased the blood viscosity. CONCLUSION TFGs has the protective effects on acute cerebral ischemia.

关键词

胡芦巴/脑缺血/凝血时间/血小板聚集/血粘度

分类

医药卫生

引用本文复制引用

李琳琳,冉新建,毛新民,王雪飞,张杰,王飞..胡芦巴总皂苷对脑缺血保护作用[J].中国药理学通报,2001,17(1):92-94,3.

中国药理学通报

OA北大核心CSCD

1001-1978

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