| 注册
首页|期刊导航|北京师范大学学报(自然科学版)|新肾显像剂99mTc-TTHA的制备和生物分布

新肾显像剂99mTc-TTHA的制备和生物分布

宋文娇 吴战宏 王学斌 陆丽仪

北京师范大学学报(自然科学版)2001,Vol.37Issue(1):92-95,4.
北京师范大学学报(自然科学版)2001,Vol.37Issue(1):92-95,4.

新肾显像剂99mTc-TTHA的制备和生物分布

THE PREPARATION AND BIO-DISTRIBUTION OF NEW KIDNEY IMAGING AGENT 99mTc-DTPA

宋文娇 1吴战宏 1王学斌 1陆丽仪1

作者信息

  • 1. 北京师范大学化学系,100875,北京
  • 折叠

摘要

Abstract

Labelling condition with 99mTc and kit preparation oftriethylene-tetraminehexaacetic acid (TTHA) are preliminarily studied. The bio-distribution of TTHA kit is compared with that of DTPA kit. The best condition of TTHA labeling in neutral solution (pH=6~7) is found, and the labeling yield is above 98%. Bio-distribution studies in mice show that the behavior of TTHA kit and DTPA kit is very similar. But compared the data carefully, 99mTc-TTHA is a littler better than 99mTc-DTPA. Further study is needed.

关键词

放射性药物/肾显像剂/99mTc标记放射性药物/三乙四胺六醋酸

分类

医药卫生

引用本文复制引用

宋文娇,吴战宏,王学斌,陆丽仪..新肾显像剂99mTc-TTHA的制备和生物分布[J].北京师范大学学报(自然科学版),2001,37(1):92-95,4.

北京师范大学学报(自然科学版)

OA北大核心CSCD

0476-0301

访问量0
|
下载量0
段落导航相关论文