北京师范大学学报(自然科学版)2001,Vol.37Issue(1):92-95,4.
新肾显像剂99mTc-TTHA的制备和生物分布
THE PREPARATION AND BIO-DISTRIBUTION OF NEW KIDNEY IMAGING AGENT 99mTc-DTPA
摘要
Abstract
Labelling condition with 99mTc and kit preparation oftriethylene-tetraminehexaacetic acid (TTHA) are preliminarily studied. The bio-distribution of TTHA kit is compared with that of DTPA kit. The best condition of TTHA labeling in neutral solution (pH=6~7) is found, and the labeling yield is above 98%. Bio-distribution studies in mice show that the behavior of TTHA kit and DTPA kit is very similar. But compared the data carefully, 99mTc-TTHA is a littler better than 99mTc-DTPA. Further study is needed. 关键词
放射性药物/肾显像剂/99mTc标记放射性药物/三乙四胺六醋酸分类
医药卫生引用本文复制引用
宋文娇,吴战宏,王学斌,陆丽仪..新肾显像剂99mTc-TTHA的制备和生物分布[J].北京师范大学学报(自然科学版),2001,37(1):92-95,4.