中国中西医结合杂志2001，Vol.21Issue(2)：94-98,5.
养精汤促排卵的临床及实验研究
Clinical and Experimental Study on the Ovulation Promoting Effect of Yangjing Decoction
刘金星 1刘敏如 2宋韬 3陆华 2唐永淑 4谭万信2
作者信息
- 1. 山东中医药大学附属医院(济南250011)
- 2. 成都中医药大学(成都610075)
- 3. 四川省计划生育研究所
- 4. 成都中医药大学附属医院
- 折叠
摘要
Abstract
Objective: To observe the effect of Yangjing Decoction (YJD) topromote ovulation and to explore its mechanism. Methods: The clinical effect of YJD in treating patients of functional non-ovulation and changes of gonadotropic hormone, sex hormone and diameter of main follicle before and after treatment were observed. In experimental study, the influence of YJD on monoamine neurotransmitter of hypothalamus, endorphin (β-EOP), serum sex hormone, trace element, endometrium and histomorphology of ovary were observed. Results: In the 36 patients observed clinically, the ovulation rate was 61.1%, the serum contents of follicular stimulation hormone (FSH), luteinizing hormone (LH) and estradiol (E2) increased and the diameter of main follicle enlarged significantly after treatment (P＜0.01, P＜0.001). The experimental study showed that the totals of follicle at different levels, the corpus luteum and the proportion of superior follicle in ovary were improved obviously in the YJD group as compared with those in the control group. After YJD treatment the hypothalamus contents of monoamine neurotransmitter, including norepinephrine (NE) and dopamine (DA) increased, the 5-hydroxytryptamine (5-HT) 5-hydroxyindoleaceticacid (5-HIAA) and β-EOP decreased significantly, and the NE/DA ratio and NE/5-HT ratio elevated obviously (P＜0.05, P＜0.001). The serum levels of E2 , P and trace elements, including Zn, Cu and Fe increased significantly (P＜0.05, P＜0.01). Conclusion: YJD is an effective recipe in promoting ovulation, the effect may be achieved through the multi-linked, multi-systemetic synthetic effect of hypothalamus, hypophysis and ovary, etc.关键词
填补肾精/促排卵/无排卵/促卵泡素/雌二醇/去甲肾上腺素/β-内啡肽分类
医药卫生引用本文复制引用
刘金星,刘敏如,宋韬,陆华,唐永淑,谭万信..养精汤促排卵的临床及实验研究[J].中国中西医结合杂志,2001,21(2):94-98,5.
