中国康复理论与实践2007，Vol.13Issue(10)：957-959,封3,4.
采用独立分量分析观察经皮穴位电针刺激对脑功能的影响
Effects of Transcutaneous Electrical Acupoint Stimulation on Brain Function Explored with Independent Component Analysis
魏鹏绪 1卢虎英 1徐基民1
作者信息
- 1. 中国康复研究中心北京博爱医院中医康复科,首都医科大学康复医学院,北京市,100068,中国
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摘要
Abstract
Objective To explore fMRI data with independent component analysis (ICA) in order to investigate effects of transcutaneous electrical acupoint stimulation (TEAS) on brain function. Methods The experiment was performed on a whole-body 1.5 T GE Signa Excite MRI scanner with which the brain oxygenation level dependent (BOLD)/EPI images were acquired from a female traumatic brain injury patient. A block designed protocol was used. Both durations of rest and TEAS were 30 seconds. The data processing was performed with GIFT, Statistical Parametric Mapping 5 (SPM5) and MRIcro. Results from ICA and SPM were compared. Results Extended Infomax algorithm provided by GIFT found thirteen independent components (ICs), each of which contained a spatial map and a corresponding time course. The spatial maps associated with task-related ICs resembled the activation maps from SPM5 but were not totally identical. In addition, the time courses of these ICs differed from the shape of canonical HRF model used by SPM. Conclusion ICA is a good choice to investigate data and obtain prior knowledge before using model-based methods such as SPM.关键词
独立分量分析/经皮穴位电刺激/功能性磁共振/统计参数图软件Key words
independent component analysis (ICA)/ transcutaneous electrical acupoint stimulation (TEAS)/ functional magnetic resonance imaging (fMRI)/statistical parametric mapping (SPM)分类
医药卫生引用本文复制引用
魏鹏绪,卢虎英,徐基民..采用独立分量分析观察经皮穴位电针刺激对脑功能的影响[J].中国康复理论与实践,2007,13(10):957-959,封3,4.
