中山医科大学学报2001，Vol.22Issue(2)：97-99,3.
体外反搏对犬失血性休克的作用机制
The Mechanism of ECP Therapy for Haemorrhagic Shock in Canine
摘要
Abstract
【Objective】 To study the protective mechanism of externalcounterpulsation(ECP) on haemorragic shock. 【Methods】 The model of severe haemorrhagic shock was used. After the whole experiment, tissue from heart and aorta were obtained to detect NOS, SOD, MDA, ATP, glycogen and lactic acid. NOS activity was detected by isotope method. 【Results】 NOS and SOD activities of the sham operation control group(SOCG) and the external counterpulsation group(ECPG) were significantly higher than those of Haemorrhagic Shock group(HSG). MDA level of SOCG was significantly lower than that of HSG and ECPG, but there was no significant difference between HSG and ECPG. The ATP levels of SOCG and ECPG were significantly higher than that of HSG. The glycogen concentration of SOCG was significantly higher than that of HSG, but there was no significant difference between HSG and ECPG. 【Conclusion】 ECP can increase NOS and SOD activities and also it can improve the energy supply of heart.关键词
休克/治疗/反搏动术/一氧化氮合酶/超氧化物歧化酶分类
医药卫生引用本文复制引用
谭红梅,蒋涛,顾熊飞,罗汉川,郑振声,吴伟康..体外反搏对犬失血性休克的作用机制[J].中山医科大学学报,2001,22(2):97-99,3.基金项目
国家自然科学基金资助项目 （）
