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胰肾联合移植治疗2型糖尿病合并终末期肾病1例

田伯乐 张肇达 刘续宝 胡伟明 韩方海 麦刚 赵继春 王莉 陆慧敏 张懿

中国组织工程研究与临床康复2009,Vol.13Issue(5):979-982,4.
中国组织工程研究与临床康复2009,Vol.13Issue(5):979-982,4.

胰肾联合移植治疗2型糖尿病合并终末期肾病1例

Simultaneous pancreas-kidney transplantation for type 2 diabetes mellitus complicated with endstaged renal disease in 1 case

田伯乐 1张肇达 1刘续宝 1胡伟明 1韩方海 1麦刚 1赵继春 1王莉 1陆慧敏 1张懿1

作者信息

  • 1. 四川大学华西医院肝胆胰外科,四川省成都市,610041
  • 折叠

摘要

Abstract

We performed a simultaneous pancreas-kidney transplantation (SPK) for type 2 diabetes complicated with end-staged renal disease (ESRD) in March, 2007. The recipient was a 65-year old male, who suffered type 2 diabetes for 15 years and renal dysfunction for 5 years and other diabetic complications such as retinopathy and peripheral neuropathy. SPK was performed successfully for him, in which the kidney was placed in the left iliac fossa, while the pancreas in the right iliac fossa, with an entedc drainage for pancreas exocrine and a systemic drainage for endocrine. Serum C-peptide, creatinine and blood urea nitrogen reached normal levels on day 1,4 and 11 post-transplant, respectively. Blood glucose became stabilized gradually to normal level and therefore the injected insulin was stopped on day 16 post-transplant. Oral glucose tolerance test (OGTT) showed the function of grafted pancreas was normal after 3 weeks of transplant, and no transplant-related complications occurred. With the recipient followed up for 20 months, both his blood glucose level and renal function maintained normal without using insulin.

关键词

胰肾联合移植/糖尿病/终末期肾病

分类

医药卫生

引用本文复制引用

田伯乐,张肇达,刘续宝,胡伟明,韩方海,麦刚,赵继春,王莉,陆慧敏,张懿..胰肾联合移植治疗2型糖尿病合并终末期肾病1例[J].中国组织工程研究与临床康复,2009,13(5):979-982,4.

基金项目

四川大学华西医院新技术开发基金资助项目(20060127) (20060127)

中国组织工程研究与临床康复

OA北大核心CSCDCSTPCD

2095-4344

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