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TRH在蓝斑复合核对血压和心率的影响及其机制

夏保芦 杨友华 杨敏 杨荣

咸宁医学院学报2001,Vol.15Issue(2):98-100,3.
咸宁医学院学报2001,Vol.15Issue(2):98-100,3.

TRH在蓝斑复合核对血压和心率的影响及其机制

Effects of TRH at Locus Caeruleus Complex Area on Blood Pressure and Heart Rate and Its Mechanism

夏保芦 1杨友华 1杨敏 1杨荣1

作者信息

  • 1. 武汉市职工医学院生理学教研室,
  • 折叠

摘要

Abstract

Objective To research the effect of TRH at locus caeruleus complex area (Lc-Sc) on blood pressure and heart rate and its mechanism.Methods The experiments were carried out on 33 anaesthetized,paralyzed and artificially ventilated rabbits.Intranuclear microinjection was adopted in this experiment.Results It was found microinjection of TRH into Lc-Sc induced a marked elevation of blood pressure and increased in heart rate.The above-mentioned effects of TRH could be blocked by preinjection α1 or β receptor-antagonist in the nucleus tractus solitarii(NTS).Conclusion TRH can excite cardiovascular activities in the Lc-Sc and this effects may be mediated by α1 or β receptors in NTS.

关键词

TRH/蓝斑复合核/孤束核/血压/心率

分类

医药卫生

引用本文复制引用

夏保芦,杨友华,杨敏,杨荣..TRH在蓝斑复合核对血压和心率的影响及其机制[J].咸宁医学院学报,2001,15(2):98-100,3.

咸宁医学院学报

2095-4646

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