安徽农业科学2009，Vol.37Issue(21)：9830-9831,9848,3.
3,13-酯基中乌头碱衍生物的合成及其杀虫活性的研究
Synthesis and Insecticidal Activity of Derivants of 3,13-Ester Mesaconitine
摘要
Abstract
[Objective]The experiment aimed to explore the relation between structure of aconitine, aconitine derivatives and insecticide. [Method]The aconitine derivatives such as 3-acetyl mesaconitine, 3-propionyl mesaconitine, 3-acetyl-13-Benzoyl-mesaconitine and 3-propionyl-13-Benzoyl-mesaconitine were synthesized by mesaconitine with acetic anhydride or propionic anhydride and their insecticidal activities were also determined. [Result]When the concentration was 500 mg/L, the insecticidal activities of mesaconitine against Nilaparvata legen and Aphis were 50% and 30% respectively while the insecticidal activities of 3-acetyl mesaconitine, 3-propionyl mesaconitine, 3-acetyl-13-Benzoyl-mesaconitine and 3-propionyl-13-Benzoyl-mesaconitine against Aphis medicagini were 40%,30%,30% and 20% respectively at 500 mg/L. [Conclusion]After hydroxyl esterification, the insecticidal activity of mesaconitine was declined and the existence of hydroxyl at 3rd position in mesaconitine played very important influences on insecticidal activity.关键词
中乌头碱/衍生物/结构/杀虫活性Key words
Mesaconitine/Derivative/Structure/Insecticidal activity分类
农业科技引用本文复制引用
王晓东,袁小红,杨海君,侯大斌,王惠,许源..3,13-酯基中乌头碱衍生物的合成及其杀虫活性的研究[J].安徽农业科学,2009,37(21):9830-9831,9848,3.基金项目
国家十一五科技支撑计划重大专项课题(2006BAE01A01-12). （2006BAE01A01-12）
