中德临床肿瘤学杂志（英文版）2005，Vol.4Issue(2)：99-101,3.
肺癌中E-钙粘蛋白的表达与微血管密度的关系及意义
Relationship between the Expression of E-cadherin and Microvessel Density in Lung Cancer and Its Significance
摘要
Abstract
Objective: To study the relationship between the expression of E-cadherin and microvessel density (MVD) in lung cancer. Methods: The expression of E-cadherin and factor Ⅷ was detected in 104 lung cancer tissues by an immunohistochemical method, and MVD was calculated by an imageanalysis system. Results: The expression of E-cadherin was significantly related to the differentiation of lung cancers (P＜0.05). A negative correlation was found between E-cadherin expression and MVD in lung cancer tissues (P=0.047). Conclusion: Down-expression of E-cadherin and an increase of MVD may play an important role in the invasion and metastasis of lung cancer, and may also be used as a useful marker for tumor prognosis.关键词
肺肿瘤/E钙粘蛋白/微血管密度Key words
lung neoplasms/E-cadherin/microvessel density引用本文复制引用
王新允,王爱香,孙翠云,杨菊红,马莹,程波,郑宏伟,郑海燕,朱丛中,刘婷,李艳..肺癌中E-钙粘蛋白的表达与微血管密度的关系及意义[J].中德临床肿瘤学杂志（英文版）,2005,4(2):99-101,3.基金项目
This study is a key project of Tianjin Scientific Committee (No. 033804211). （No. 033804211）
