中华医学杂志（英文版）2010，Vol.123Issue(5)：581-584,4.DOI:10.3760/cma.j.issn.0366-6999.2010.05.014
Morphologic characteristics of late stent malapposition after drug-eluting stents implantation by optical coherence tomography follow-up
Morphologic characteristics of late stent malapposition after drug-eluting stents implantation by optical coherence tomography follow-up
HOU Jing-bo 1LIU Hui-min 2MA Li-jia 1YANG Shuang 2MENG Ling-bo 1HAN Zhi-gang 2ZHANG Shuo 1YU Bo2
作者信息
- 1. Department of Cardiology,Second Affiliated Hospital of Harbin Medical University
- 2. Key Laboratories of Education Ministry for Myocardial Ischemia Mechanism and Treatment,Harbin,Heilongjiang 150086,China
- 折叠
摘要
Abstract
Background Late stent malapposition was frequently observed after DES implantation, which has been associated with the occurrence of late stent thrombosis due to poor neointimal coverage. This study was designed to evaluate the frequency of late stent malapposition at least 1 year after different DESs implantation by optical coherence tomography (OCT). Methods Angiographic and OCT examinations were given to 68 patients who had received total 126 various DESs implantation for at least 1 year to detect late stent malapposition. Malapposed strut distance (MSD), malapposed strut area (MSA), reference lumen area (RLA) and reference stent area (RSA) were checked with off-line OCT analysis. Results Totally 26 Cypher Select stents, 15 Taxus Liberte stents, 51 Partner stents and 34 Firebird I stents were examined. Among 68 patients who underwent DES implantation, 7 patients (10.3%) had late malapposition. Average RSA, MSA and MSD were (7.9±2.8)mm~2,(2.0±1.6)mm~2 and (590±270)μm respectively.According to the MSA/RSA ratio,4 patients had slight malapposition,2 patients had moderate malapposition and 1 patient had severe malapposition.Conclusions Late stent malapposition is detected frequently after implantation of DES,but if this predisposes to late stent thrombosis and requires any specific therapy needs to be further elucidated. 关键词
drug-eluting stent/late stent malapposition/very late stent thrombosis/optical coherence tomographyKey words
drug-eluting stent/late stent malapposition/very late stent thrombosis/optical coherence tomography引用本文复制引用
HOU Jing-bo,LIU Hui-min,MA Li-jia,YANG Shuang,MENG Ling-bo,HAN Zhi-gang,ZHANG Shuo,YU Bo..Morphologic characteristics of late stent malapposition after drug-eluting stents implantation by optical coherence tomography follow-up [J].中华医学杂志（英文版）,2010,123(5):581-584,4.
