中华医学杂志（英文版）2010，Vol.123Issue(5)：559-562,4.DOI:10.3760/cma.j.issn.0366-6999.2010.05.010
Analysis of risk factors of surgical site infections in breast cancer
Analysis of risk factors of surgical site infections in breast cancer
GAO Yang-xu 1XU Ling 1YE Jing-ming 1WANG Dong-min 1ZHAO Jian-xin 1ZHANG Lan-bo 1DUAN Xue-ning 1LIU Yin-hua1
作者信息
- 1. Center of Breast Disease,Peking University First Hospital,Beijing 100034,China
- 折叠
摘要
Abstract
Background Adjuvant chemotherapy has become an important component of standard therapy for breast cancer. However, until now, there have been few reports on the surgical site infections (SSI) after breast cancer surgery, specially after adjuvent chemotherapy. To study the risk factors of SSI of breast cancer, we analyzed patients diagnosed with breast cancer and treated with surgery. Methods Fifty-five patients diagnosed with breast cancer and received breast conserving or modified radical operations in our hospital during January 2008 to March 2008 were selected. Factors (patients' age, body mass index (BMI), diabetes mellitus, no or administered adjuvant chemotherapy, with or without onset of myelosuppression and the degree, surgical approaches, duration of operation, postoperative drainage duration and total drainage volume) associated with SSI were retrospectively reviewed and statistically analyzed by single factor analysis. Results Five patients suffered SSI (5/55, 9.1%); nineteen receiving adjuvant chemotherapy experienced Grade III+ myelosuppression, among which 4 had SSI; only 1 out of the remaining 36 patients without adjuvant chemotherapy had SSI. The difference between the two groups was significant (P=0.043). The incidence of SSI in patients with postoperative drainage tube indwelling longer than 10 days was 5/21, whereas no SSI occurred in that less than 10 days (R=0.009). in our study, there was no significient difference in other associated factors. Conclusions Concurrent Grade III+ myelosuppression after adjuvant chemotherapy is an important risk factor of SSI in breast cancer and needs further study. No SSI was detected with indwelling time of post operative drainage less than 10 days. 关键词
breast cancer/adjuvant treatment/surgical site infectionKey words
breast cancer/adjuvant treatment/surgical site infection引用本文复制引用
GAO Yang-xu,XU Ling,YE Jing-ming,WANG Dong-min,ZHAO Jian-xin,ZHANG Lan-bo,DUAN Xue-ning,LIU Yin-hua..Analysis of risk factors of surgical site infections in breast cancer [J].中华医学杂志（英文版）,2010,123(5):559-562,4.
