首页|期刊导航|中华医学杂志（英文版）|Preoperative 3T high field blood oxygen level dependent functional magnetic resonance imaging for glioma involving sensory cortical areas
中华医学杂志（英文版）2010，Vol.123Issue(8)：1006-1010,5.DOI:10.3760/cma.j.issn.0366-6999.2010.08.006
Preoperative 3T high field blood oxygen level dependent functional magnetic resonance imaging for glioma involving sensory cortical areas
Preoperative 3T high field blood oxygen level dependent functional magnetic resonance imaging for glioma involving sensory cortical areas
摘要
Abstract
Background Localization of sensory cortical areas during the operation is essential to preserve the sensory function.Intraoperative direct electrostimulation under awake anesthesia is the golden standard but time-consuming. We applied 3T high field blood oxygen level-dependent (BOLD) functional magnetic resonance imaging (fMRI) to identify the relationship between glioma and cortical sensory areas preoperatively and to guide intraoperative direct electrostimulation for quick and precise localization.Methods Five glioma patients with sensory cortex involvement by or next to the lesion had preoperative BOLD fMRI to determine the spatial relationship of cortical sensory areas to the tumours. Bilateral hand opposite movement was performed by these patients for fMRI. Precentral and postcentral gyri were identified by electrical stimulation during the operation. Karnofsky Performance Status scores of the patients' pre- and postoperative and the role of BOLD fMRI were evaluated.Results The cortical sensory areas were all activated in five glioma patients involving postcentral gyrus areas by BOLDf MRI with bilateral hand opposite movement. The detected activation areas corresponded with the results from cortical electrical stimulation.Conclusions The relationship between cortical sensory areas and tumour can be accurately shown by BOLD fMRI before operation. And the information used to make the tumour resection could obtain good clinical results.关键词
functional magnetic resonance imaging/somatosensory area/awake anesthesia/cortical stimulationKey words
functional magnetic resonance imaging/somatosensory area/awake anesthesia/cortical stimulation引用本文复制引用
LI Shao-wu,WANG Jiang-fei,JIANG Tao,LI Shou-wei,ZHANG Wen-bo,LI Zi-xiao,ZHANG Zhong,DAI Jian-ping,WANG Zhong-cheng..Preoperative 3T high field blood oxygen level dependent functional magnetic resonance imaging for glioma involving sensory cortical areas[J].中华医学杂志（英文版）,2010,123(8):1006-1010,5.基金项目
This work was supported by a grant from the country "11th Five-Year Plan" (No. 2007BAI05B08), Major Program of the National Natural Science Foundation of China (No. 30730035) and Key Project of Chinese National Programs for Fundamental Research and Development (973 Program, No.2007CB512500). （No. 2007BAI05B08）
