国际医药卫生导报2010,Vol.16Issue(18):2253-2255,3.DOI:10.3760/cma.j.issn.1007-1245.2010.18.022
氢氯吡格雷与辛伐他汀联合治疗急性冠脉综合征的疗效观察
The efficacy of clopidogrel combined with simvastatin for acute coronary syndrome
摘要
Abstract
Objective To explore the efficacy of clopidogrel combined with simvastatin for acute coronary syndrome (ACS). Methods 64 patients with ACS in our hospital from January 2007 to May 2009 were randomly assigned to receive conventional therapies (control group) or combination therapy with clopidogrel and simvastatin (study group). Results The decrease in hs-CRP level was markedly greater in the study group than in the control group (P<0.05). The reduction in blood lipids did not differ significantly between the two groups (P>0.05). The rates of platelet aggregation,recurrence of angina pectoris,and rehospitalization were significantly lower in the study group than in the control group (P<0.05 for all comparisons). No obvious adverse reactions were found in the two groups. Conclusions Combination therapy with clopidogrel and simvastatin is effective in the treatment of acute coronary syndrome.关键词
氢氯吡格雷/辛伐他汀/急性冠脉综合征Key words
Clopidogrel/Simvastatin/Acute coronary syndrome引用本文复制引用
黄宇,龙伟东,陈朝阳,林土坤..氢氯吡格雷与辛伐他汀联合治疗急性冠脉综合征的疗效观察[J].国际医药卫生导报,2010,16(18):2253-2255,3.