国际医药卫生导报2010，Vol.16Issue(14)：1677-1680,4.DOI:10.3760/cma.j.issn.1007-1245.2010.14.004
ER、PR、Ki-67在绝经后子宫内膜病变中的表达
Expressions of estrogen receptors, progensterone receptors, and Ki-67 in endometrial diseases in post-menopausal women
摘要
Abstract
Objective To explore the relationship between endometrial polyps and endometrial carcinoma in postmenopausal woman.Methods 35 samples of atrophic endometrial tissues,30 of endometrial polyps,and 32 of endometrial carcinoma were collected.The expressions of ER,PR,and Ki-67 were detected by immunohistochemical assay.Results The expressions of ER and PR were significantly higher in the polyps tissues than in the atrophic endometrial tissues and the cancerous tissues (P<0.05).Ki-67 expression increased gradually in the three different types of tissues (P<0.05).Conclusions An elevation in ER and PR plays a major role in the development of postmenopause-induced endometrial polyps.The overexpression of Ki-67 in endometrial polyps may predict of carcinogenesis from polyps.关键词
绝经后子宫内膜/绝经后子宫内膜息肉/绝经后子宫内膜癌/免疫组织化学/Ki-67/ER/PRKey words
Postmenopausal endometrium/Postmenopausal endometrial polyps/Postmenopausal endometrial carcinoma/ER/PR/Ki-67引用本文复制引用
黄凯清,梁立治,彭文明..ER、PR、Ki-67在绝经后子宫内膜病变中的表达 [J].国际医药卫生导报,2010,16(14):1677-1680,4.基金项目
2009年广东省社会发展领域科技计划项目(93065) （93065）
