摘要
Abstract
Objective To explore the effects of fentanyl and tramadol on restlessness during consciousness phase after remifentanil-based general anesthesia. Methods 120 ASA II patients undergo- ing elective laparoscopic surgery under general anesthesia were randomly assigned to group Q1, Q2, Q3, F1, F2, or F3 with 20 each. 30 min before the end of the procedure, tramadol of 1, 2, or 3 mg/kg was administered to group Q1, Q2, or Q3. so was fentanyl of 0.1, 0.2, or 0.3 μ,/kg to groups F1, F2, and F3. SBP, DBP, MAP, HR, SpO2, and PftCO2 were recorded. Restlessness Score (RS), Ramsay Sedation Score (RSS), Observer's Assessment of Alertness/Sedation Score (OAAS) were recorded before, during, and 10 min after extubation. Body side reaction were observed. Results RS was apparently higher in groups Q1 and Q2 than in group Q3 before, (luring, and 10 min after extuhation (P<0.05). RS in group Q1 was apparently higher than that in groups F1, F2. and F3(P<0.05). RSS in groups Q1 and Q2 was apparently higher than that in group Q3 before, during, and 10 min after extuhation ({<0.05). RSS in groups Q1, Q2. and Q3 was apparently higher than that in groups F1, F2, and F3 (P<0.05). OASS in groups Q1 and Q2 was apparently higher than that in group Q3 before, during, and 10 min after extubation (P<0.05). OASS in group Q3 was apparently higher than that in groups F1, F2, and F3 (P<0.05). The major side effects in group F3 were respiratory depression and circulatory system. Conclusions Application of 0.3 μ g/kg fentany can safely and perfectly prevent restlessness during consciousness phase after remifentanil-based general anesthesia, and has fewer side effects.关键词
曲马多/芬太尼/苏醒期躁动Key words
Fentanyl/Tramadol/Restlessness/Prevention
