首页|期刊导航|中国神经再生研究（英文版）|Evaluation of non-typical diffuse axonal injury by magnetic resonance techniques
中国神经再生研究（英文版）2010，Vol.5Issue(17)：1337-1341,5.DOI:10.3969/j.issn.1673-5374.2010.17.010
Evaluation of non-typical diffuse axonal injury by magnetic resonance techniques
Evaluation of non-typical diffuse axonal injury by magnetic resonance techniques
摘要
Abstract
Because diffuse axonal injury(DAI)lacks specific clinical manifestations,it is difficult to evaluate DAI using computer tomography or conventional magnetic resonance imaging(MRI).This study investigated the value of magnetic resonance techniques using fluid-attenuated inversion recovery(FLAIR)and proton magnetic resonance spectroscopy(1HMRS)for diagnosing DAI.The corpus callosum and basal nuclei were analyzed using morphological and functional imaging.Similar to the DAI group,the non-typical DAI group exhibited similar lesion characteristics on FLAIR,as well as post-injury neurochemical and molecular changes in the corpus callosum,as detected by 1HMRS.However,there were differences in degree and severity of injury.Compared to conventional MRI,FLAIR significantly increased lesion detection.1HMRS determined biochemical metabolism changes in midline structures following DAI,which resulted in increased diagnosis of non-typical DAI,which displayed similar lesion distribution,morphology,and function as DAI.Thus,the experiment proved the value of FLAIR and 1HMRS in non-typical DAI.关键词
diffuse axonal injury/magnetic resonance imaging/magnetic resonance spectroscopy/case-control study/traumatic brain injuryKey words
diffuse axonal injury/magnetic resonance imaging/magnetic resonance spectroscopy/case-control study/traumatic brain injury分类
医药卫生引用本文复制引用
Haijian Xia,Xiaochuan Sun,Zongduo Guo,Weidong Fang,Fajin Lü,Haitao Wu,Tianyou Luo,Wenyuan Tang..Evaluation of non-typical diffuse axonal injury by magnetic resonance techniques[J].中国神经再生研究（英文版）,2010,5(17):1337-1341,5.基金项目
Supported by:the Grant from Chongqing Board of Health,No.2009-2-391,No.06-2-175 （）
the Grant from Chongqing Medical University,No.XBYB2007005 （）
