中国神经再生研究（英文版）2010，Vol.5Issue(18)：1408-1412,5.DOI:10.3969/j.issn.1673-5374.2010.18.008
Electroacupuncture-attenuated ischemic brain injury increases insulin-like growth factor-1expression in a rat model of focal cerebral ischemia
Electroacupuncture-attenuated ischemic brain injury increases insulin-like growth factor-1expression in a rat model of focal cerebral ischemia
Huanmin Gao 1Ling Wang 2Yunliang Guo3
作者信息
- 1. Department of Neurology,Second Affiliated Hospital,Qingdao University Medical College,Qingdao 266042,Shandong Province,China
- 2. Shandong Province Key Laboratory of Brain Disease Prevention and Treatment,Institute of Cerebral Vascular Diseases of Qingdao University Medical College,Qingdao 266003,Shandong Province,China
- 折叠
摘要
Abstract
Acupuncture has recently gained popularity in many countries as an alternative and complementary therapeutic intervention.Previous studies have shown that changes in genes,proteins,and their metabolites were measureable during acupuncture for treatment of cerebral ischemia.Through the use of in situ hybridization and immunohistochemistry,the present study confirmed that electroacupuncture increased insulin-like growth factor-1 mRNA and protein expression in the corpus striatum following cerebral ischemia,reduced brain edema following middle cerebral artery occlusion repeffusion,and decreased infarct volume.Results suggested that electroacupuncture is effective in the relief of cerebral ischemia by increasing endogenous insulin-like growth factor-1 expression.关键词
electroacupuncture/cerebral ischemia/focal/insulin-like growth factor-1/brain injury/neural regenerationKey words
electroacupuncture/cerebral ischemia/focal/insulin-like growth factor-1/brain injury/neural regeneration分类
医药卫生引用本文复制引用
Huanmin Gao,Ling Wang,Yunliang Guo..Electroacupuncture-attenuated ischemic brain injury increases insulin-like growth factor-1expression in a rat model of focal cerebral ischemia[J].中国神经再生研究（英文版）,2010,5(18):1408-1412,5.
